{"id":4137,"date":"2024-08-02T09:52:12","date_gmt":"2024-08-02T01:52:12","guid":{"rendered":"\/\/www.rushplease.com\/?p=4137"},"modified":"2024-08-02T09:52:12","modified_gmt":"2024-08-02T01:52:12","slug":"trost-chen%e9%85%b8%e9%85%90%e8%84%b1%e7%be%a7%e5%8f%8d%e5%ba%94","status":"publish","type":"post","link":"\/\/www.rushplease.com\/archives\/4137","title":{"rendered":"Trost-Chen\u9178\u9150\u8131\u7fa7\u53cd\u5e94"},"content":{"rendered":"<p><a href=\"\/\/www.rushplease.com\/\" target=\"_self\" rel=\"noopener\"><strong>Trost-Chen\u9178\u9150\u8131\u7fa7<\/strong><\/a>\u53cd\u5e94<\/p>\n<p>\u4e01\u4e8c\u9178\u9150\u7c7b\u5316\u5408\u7269\u5728\u954d\u50ac\u5316\u4e0b\u52a0\u70ed\u8131\u7fa7\u751f\u6210\u70ef\u70c3\u7684\u53cd\u5e94\u3002<\/p>\n<p>\u954d\u50ac\u5316Suzuki\u5076\u8054\u53cd\u5e94<\/p>\n<p>Syun Satio\u7b49\u7814\u7a76\u53d1\u73b0,\u5728\u96f6\u4ef7\u954d\u50ac\u5316\u4e0b\u6c2f\u4ee3\u82b3\u70c3\u548c\u82b3\u57fa\u787c\u9178\u572880\u2103\u53ef\u9ad8\u4ea7\u7387\u5730\u53d1\u751f\u5076\u8054\u53cd\u5e94\uff0c\u96f6\u4ef7\u954d\u81eaNiCl2(dppf) \uff0810 mol%\uff09\u548cn-BuLi(40mol%)\u201c\u4e00\u9505\u201d\u53cd\u5e94\u6765\u5236\u5907\uff0c\u800c\u6c2f\u4ee3\u82b3\u70c3\u53ef\u5e26\u6709\u5404\u79cd\u5438\u7535\u5b50\u6216\u7ed9\u7535\u5b50\u57fa\u56e0. \u6b64\u65b9\u6cd5\u4e2d\u954d\u50ac\u5316\u5242\u6210\u672c\u4f4e\uff0c\u540c\u65f6\u9009\u7528\u5ec9\u4ef7\u7684\u6c2f\u4ee3\u82b3\u70c3\u4f5c\u4e3a\u53cd\u5e94\u7269\uff0c\u56e0\u800c\u6709\u5f88\u9ad8\u7684\u5de5\u4e1a\u5e94\u7528\u4ef7\u503c\uff1b\u4e5f\u6709\u4eba\u7814\u7a76\u4f7f\u7528NiCl2(PPh3)2\u6765\u50ac\u5316\u70f7\u57fa\u53d6\u4ee3\u787c\u9178\u76d0\u548c\u6eb4\u4ee3\u7269\u7684\u5076\u53d6\u53cd\u5e94\uff0c\u5728\u5ba4\u6e29\u4e0b\u4ee580%\u7684\u9ad8\u4ea7\u7387\u5408\u6210\u4e86\u751f\u7269\u6d3b\u6027\u5316\u5408\u7269\u3002<\/p>\n<p><img decoding=\"async\" class=\"alignnone size-full wp-image-4138\" src=\"\/\/www.rushplease.com\/wp-content\/uploads\/2024\/08\/1685172604168.jpg\" width=\"300\" height=\"261\" srcset=\"\/\/www.rushplease.com\/wp-content\/uploads\/2024\/08\/1685172604168.jpg 300w, \/\/www.rushplease.com\/wp-content\/uploads\/2024\/08\/1685172604168-220x191.jpg 220w\" sizes=\"(max-width: 300px) 100vw, 300px\" title=\"Trost-Chen\u9178\u9150\u8131\u7fa7\u53cd\u5e94\u63d2\u56fe\" alt=\"Trost-Chen\u9178\u9150\u8131\u7fa7\u53cd\u5e94\u63d2\u56fe\" \/><\/p>\n<p>Yamamoto \u5076\u8054<\/p>\n<p>Yamamoto\u5076\u8054 (Yamamoto coupling)\u53c8\u79f0\u4e3aYamamoto\u805a\u5408 (Yamamoto polymerization)\uff0c\u662f\u8fc7\u6e21\u91d1\u5c5e\u8bd5\u5242 (\u5982PdCl2(bipy), NiCl2(bipy), Ni (cod)2,NiBr2(PPh2)2, NiCl2, CoCl2, FeCl2\u7b49\uff0c\u5176\u4e2dNiCl2(bipy)\u4e0eNi (cod)2\u4e3a\u5e38\u7528)\u4fc3\u8fdb\u7684\u4e8c\u5364\u4ee3\u82b3\u70c3\u4e0e\u591a\u5364\u4ee3\u82b3\u70c3\u901a\u8fc7\u53bb\u5364\u5316\u53cd\u5e94\u800c\u8fdb\u884c\u5076\u8054\u7f29\u805a[1]\u6216\u8131\u5364C-C\u5076\u8054\u3002<\/p>\n<p>\u5e38\u89c1\u7684\u954d\u50ac\u5316\u53cd\u5e94<\/p>\n<p>\u5e38\u7528\u50ac\u5316\u5242&#8212;-\u4e8c\u6c2f\u4e8c(\u4e09\u57fa\u81a6)\u954d<\/p>\n<p>\u5e38\u7528\u8bd5\u5242&#8212;-\u6c2f\u5316\u954d<\/p>\n<p>\u5e38\u7528\u50ac\u5316\u5242&#8212;-Ni(COD)2 \u7684\u5e94\u7528<\/p>\n<p><img decoding=\"async\" class=\"alignnone size-full wp-image-4139\" src=\"\/\/www.rushplease.com\/wp-content\/uploads\/2024\/08\/1701515866587.jpg\" width=\"800\" height=\"600\" srcset=\"\/\/www.rushplease.com\/wp-content\/uploads\/2024\/08\/1701515866587.jpg 800w, \/\/www.rushplease.com\/wp-content\/uploads\/2024\/08\/1701515866587-350x263.jpg 350w, \/\/www.rushplease.com\/wp-content\/uploads\/2024\/08\/1701515866587-768x576.jpg 768w, \/\/www.rushplease.com\/wp-content\/uploads\/2024\/08\/1701515866587-220x165.jpg 220w\" sizes=\"(max-width: 800px) 100vw, 800px\" title=\"Trost-Chen\u9178\u9150\u8131\u7fa7\u53cd\u5e94\u63d2\u56fe1\" alt=\"Trost-Chen\u9178\u9150\u8131\u7fa7\u53cd\u5e94\u63d2\u56fe1\" \/><img decoding=\"async\" class=\"alignnone size-full wp-image-4140\" src=\"\/\/www.rushplease.com\/wp-content\/uploads\/2024\/08\/1701512784791.jpg\" width=\"1080\" height=\"1080\" srcset=\"\/\/www.rushplease.com\/wp-content\/uploads\/2024\/08\/1701512784791.jpg 1080w, \/\/www.rushplease.com\/wp-content\/uploads\/2024\/08\/1701512784791-350x350.jpg 350w, \/\/www.rushplease.com\/wp-content\/uploads\/2024\/08\/1701512784791-1024x1024.jpg 1024w, \/\/www.rushplease.com\/wp-content\/uploads\/2024\/08\/1701512784791-200x200.jpg 200w, \/\/www.rushplease.com\/wp-content\/uploads\/2024\/08\/1701512784791-768x768.jpg 768w, \/\/www.rushplease.com\/wp-content\/uploads\/2024\/08\/1701512784791-300x300.jpg 300w, \/\/www.rushplease.com\/wp-content\/uploads\/2024\/08\/1701512784791-220x220.jpg 220w\" sizes=\"(max-width: 1080px) 100vw, 1080px\" title=\"Trost-Chen\u9178\u9150\u8131\u7fa7\u53cd\u5e94\u63d2\u56fe2\" alt=\"Trost-Chen\u9178\u9150\u8131\u7fa7\u53cd\u5e94\u63d2\u56fe2\" \/><\/p>\n<p>\u70ef\u7094\u7c7b\u5316\u5408\u7269\u5728\u81a6\u914d\u4f4d\u7684\u94d1\u50ac\u5316\u5242\u7684\u50ac\u5316\u4e0b\u8fdb\u884c\u9ad8\u533a\u57df\u9009\u62e9\u6027\u7684\u8fdb\u884c\u4e0d\u5bf9\u79f0\u73af\u5316\u5f02\u6784\u5316\u751f\u6210\u4e94\u5143\u6742\u73af\u5316\u5408\u7269\u7684\u53cd\u5e94\u3002\u901a\u8fc7\u8be5\u53cd\u5e94\u53ef\u4ee5\u65b9\u4fbf\u5730\u5b9e\u73b0\u70ef\u70c3\u548c\u7094\u70c3\u5206\u5b50\u5185\u7684\u4e0d\u5bf9\u79f0\u73af\u5316\uff0c\u9ad8\u6548\u5730\u6784\u7b51\u4e00\u7cfb\u5217\u4e94\u5143\u6742\u73af\u5316\u5408\u7269\uff0c\u5728\u751f\u7269\u6d3b\u6027\u5206\u5b50\u4ee5\u53ca\u836f\u7269\u5206\u5b50\u7684\u5408\u6210\u4e2d\u6709\u91cd\u8981\u7684\u5e94\u7528\u30022000\u5e74\uff0c\u5f20\u7eea\u7a46\u7684\u8bfe\u9898\u7ec4\u62a5\u9053\u4e86\u9996\u4f8b\u624b\u6027\u94d1\u50ac\u5316\u5242\u50ac\u5316\u76841,6-\u70ef\u7094\u7c7b\u5316\u5408\u7269\u4e0d\u5bf9\u79f0\u73af\u5316\u5f02\u6784\u5316\u53cd\u5e94\u3002\u53cd\u5e94\u4f53\u7cfb\u4e2d\u7684\u50ac\u5316\u5242\u662f\u7531\u4e2d\u6027\u7684\u94d1\u50ac\u5316\u5242[Rh(COD)Cl]2\u4e0e\u624b\u6027\u914d\u4f53\u7ecf\u94f6\u76d0\u6d3b\u5316\u540e\u5236\u5f97\u3002<\/p>\n<p><img decoding=\"async\" class=\"alignnone size-full wp-image-4141\" src=\"\/\/www.rushplease.com\/wp-content\/uploads\/2024\/08\/1684378026217.jpg\" width=\"895\" height=\"698\" srcset=\"\/\/www.rushplease.com\/wp-content\/uploads\/2024\/08\/1684378026217.jpg 895w, \/\/www.rushplease.com\/wp-content\/uploads\/2024\/08\/1684378026217-350x273.jpg 350w, \/\/www.rushplease.com\/wp-content\/uploads\/2024\/08\/1684378026217-768x599.jpg 768w, \/\/www.rushplease.com\/wp-content\/uploads\/2024\/08\/1684378026217-220x172.jpg 220w\" sizes=\"(max-width: 895px) 100vw, 895px\" title=\"Trost-Chen\u9178\u9150\u8131\u7fa7\u53cd\u5e94\u63d2\u56fe3\" alt=\"Trost-Chen\u9178\u9150\u8131\u7fa7\u53cd\u5e94\u63d2\u56fe3\" \/><\/p>\n<p>\u7094\u94dc\u6216\u7094\u916f\u5728\u8fc7\u6e21\u91d1\u5c5e\u50ac\u5316\u5242\u6216\u53d4\u81a6\u7684\u50ac\u5316\u4e0b\u5f02\u6784\u6210E, E\u6784\u578b\u7684\u5171\u8f6d\u4e8c\u70ef\u916e\u7684\u53cd\u5e94\u3002<\/p>\n<p>\u674e\u671d\u519b\u4e09\u7ec4\u5206\u53cd\u5e94\u662f\u6307\u5728\u8fc7\u6e21\u91d1\u5c5e\u50ac\u5316\u4e0b\u919b-\u7094-\u80fa\u4e09\u7ec4\u5206\u76f4\u63a5\u8131\u6c34\u7f29\u5408\u5f97\u5230\u4e19\u7094\u80fa\u7684\u53cd\u5e94\uff0c\u53cd\u5e94\u901a\u5e38\u5728\u6c34\u4e2d\u8fdb\u884c\u30021\u20134<\/p>\n<p>\u8bb8\u591a\u50ac\u5316\u5242\u7cfb\u7edf\uff0c\u5982 [Ru]\/[Cu],5 [Au],6 [Ag],7 \u548c\u94c18,9\u90fd\u53ef\u4ee5\u5f88\u597d\u7684\u7528\u4e8e\u6b64\u53cd\u5e94\u3002<\/p>\n<p>\u7cd6\u7c7b\u5316\u5408\u726910\u201311\u4e5f\u53ef\u4ee5\u76f4\u63a5\u8fdb\u884c\u6b64\u53cd\u5e94\u751f\u6210\u4e19\u7094\u80fa\u4ea7\u7269\u3002\u5bf9\u4e8e\u4e00\u4e9b\u7279\u5b9a\u57fa\u56e2\u7684\u6c28\u57fa\u9178\u548c\u591a\u80bd\u5728\u751f\u7406\u6761\u4ef6\u4e0b\uff0c\u4e5f\u53ef\u4ee5\u8fdb\u884c\u4e09\u7ec4\u5206\u53cd\u5e9412\uff0c13 \u3002\u4f2f\u80fa14,15\u548c\u82b3\u9999\u4ef2\u80fa16\u53ef\u4ee5\u9ad8\u6548\u8fdb\u884c\u4e0d\u5bf9\u79f0\u7684\u4e09\u7ec4\u5206\u53cd\u5e94\u3002\u6b64\u53cd\u5e94\u4e5f\u9002\u7528\u4e8e\u6d41\u52a8\u5316\u5b66\u5408\u621017\u3002<\/p>\n<p>\u5728Au(\u2160)\u7edc\u5408\u7269\uff08\u5982Ph3PAuOTf\u3001Ph3PAuNTf2\uff09\u50ac\u5316\u4e0b\uff0c\u4ee5\u7cd6\u57fa\u90bb\u7094\u57fa\u7532\u9178\u916f\u4e3a\u7ed9\u4f53\u8fdb\u884c\u7cd6\u82f7\u5316\u53cd\u5e94\u3002<\/p>\n<p>Tsuji-Wilkinson\u8131\u7fb0\u57fa\u53cd\u5e94<\/p>\n<p>\u91d1\u5c5e\u50ac\u5316C-H\u6d3b\u5316(Catalytic C-H activation)<\/p>\n<p>Noyori\u4e0d\u5bf9\u79f0\u6c22\u5316\u53cd\u5e94<\/p>\n<p>\u91d1\u5c5e\u5361\u5bbe\u7684\u73af\u4e19\u70f7\u5316\u53cd\u5e94(Cyclopropanation with Metal Carbenoid)<\/p>\n<p>Kagan-Horner-Knowle\u4e0d\u5bf9\u79f0\u6c22\u5316\u53cd\u5e94<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Trost-Chen\u9178\u9150\u8131\u7fa7\u53cd\u5e94 \u4e01\u4e8c\u9178\u9150\u7c7b\u5316\u5408\u7269\u5728\u954d\u50ac\u5316\u4e0b\u52a0\u70ed\u8131\u7fa7\u751f\u6210\u70ef\u70c3\u7684\u53cd\u5e94\u3002 \u954d\u50ac\u5316Suzuki\u5076\u8054\u53cd\u5e94 Syun Satio\u7b49\u7814\u7a76\u53d1\u73b0,\u5728\u96f6\u4ef7\u954d\u50ac\u5316\u4e0b\u6c2f\u4ee3\u82b3\u70c3\u548c\u82b3\u57fa\u787c\u9178\u572880\u2103\u53ef\u9ad8\u4ea7\u7387\u5730\u53d1\u751f&#8230; <\/p>\n","protected":false},"author":2,"featured_media":4138,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[45],"tags":[],"_links":{"self":[{"href":"\/\/www.rushplease.com\/wp-json\/wp\/v2\/posts\/4137"}],"collection":[{"href":"\/\/www.rushplease.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"\/\/www.rushplease.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/\/www.rushplease.com\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"\/\/www.rushplease.com\/wp-json\/wp\/v2\/comments?post=4137"}],"version-history":[{"count":1,"href":"\/\/www.rushplease.com\/wp-json\/wp\/v2\/posts\/4137\/revisions"}],"predecessor-version":[{"id":4142,"href":"\/\/www.rushplease.com\/wp-json\/wp\/v2\/posts\/4137\/revisions\/4142"}],"wp:featuredmedia":[{"embeddable":true,"href":"\/\/www.rushplease.com\/wp-json\/wp\/v2\/media\/4138"}],"wp:attachment":[{"href":"\/\/www.rushplease.com\/wp-json\/wp\/v2\/media?parent=4137"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/\/www.rushplease.com\/wp-json\/wp\/v2\/categories?post=4137"},{"taxonomy":"post_tag","embeddable":true,"href":"\/\/www.rushplease.com\/wp-json\/wp\/v2\/tags?post=4137"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}